2 the multifocal nature of breast cancer and the imaging methods of choice

Tài liệu Voices of Fear and Safety¿ Women¿s ambivalence towards breast cancer and breast health: a qualitative study from Jordan pdf

Ngày tải lên : 13/02/2014, 06:20

... constituting 20 % of the total cancer cases and 22 % of the cancer deaths The age-standardized incidence rate of breast cancer increased from 29/100 000 in 1996 to 50/100 000 in 2008 Breast cancer comprises ... constitutes 23 % of the total new cancer cases and 14 % of the cancer deaths [1] Early detection of breast cancer makes the treatment more effective which leads to better health outcomes and higher ... issued from the Jordan Ministry of Health Research Ethics Committee in 2009 The confidentiality and autonomy of the participants was insured They were informed of the purpose of the study, the voluntary...

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Breast Cancer and the Environment potx

Ngày tải lên : 23/03/2014, 01:20

... of studies of possible risk factors, and it may influence approaches to prevention Described here are the basics of the anatomy of the breast and breast development, types of breast cancer, and ... one of the main topics in Chapter A brief description of breast cancer in men is provided in Box 2-1 The Breast, Breast Development, and Breast Cancer The development of the human female breast ... of breast cancer This growing knowledge has stimulated a transition in breast cancer research The new perspectives on breast cancer highlight the limitations of the current understanding of the...

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DO NOT DELAY: BREAST CANCER AND TIME, 1900-1970 pdf

Ngày tải lên : 06/03/2014, 00:22

... the dangers posed by breast cancer are a direct consequence of a century of ideas and practices surrounding the causes and prevention of cancer, especially breast cancer. 1 Most striking are the ... Bathe the spot thoroughly and apply a pad of antiphlogistan” (Hoffman 1913) For Hoffman and other ASCC activists, the lack of surgical attention and physical examination, the local remedies, the ... budget, and priorities See Patterson (1987), especially chapters and Breast Cancer and Time, 1900–1970 383 References Adair, F.E 1943 The Doctor Looks at Women and Their Problem of Cancer of the Breast...

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Cornell University Program on Breast Cancer and Environmental Risk Factors in New York State (BCERF) pptx

Ngày tải lên : 15/03/2014, 01:20

... other hand, smoking has been shown to have many effects which suggest an opposition of the effects of estrogen and could decrease breast cancer risk The interplay between the effects of the cancer- causing ... in breast cancer risk Most of the studies that have examined the breast cancer risk of women who have quit smoking have reported an increase in breast cancer risk In many of these studies, breast ... with the risk of death from breast cancer Smokers may be at increased risk for metastasis (the spread of cancer) Two studies have reported an increase in the spread of tumors from the breast to the...

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Báo cáo sinh học: " Genital tuberculosis in a tamoxifen-treated postmenopausal woman with breast cancer and bloody vaginal discharge" pot

Ngày tải lên : 08/08/2014, 19:20

... the hysteroscopy and endometrial aspiration biopsy of the patient SM participated in the coordination of the clinical and laboratory work-up GS conceived the report, treated the patient for the ... usually absent and there is often no evidence of TB in other organs If present, the symptoms are mild and Page of (page number not for citation purposes) Annals of Clinical Microbiology and Antimicrobials ... revealed that the patient's mother and sister had died 30 and 10 years ago from TB The patient had taken close care of both No other family members had symptoms suspicious of TB Interestingly, the patient...

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Báo cáo y học: " Multifocal invasive ductal breast cancer with osteoclast-like giant cells: a case report" doc

Ngày tải lên : 11/08/2014, 00:22

... invasive cancer Because of the multifocal character of the breast cancer, a bilateral breast magnetic resonance imaging (MRI) scan was obtained to exclude further lesions Eleven days after the woman’s ... chemotherapy Our patient was treated with continuation of adjuvant therapy with aromatase inhibitor and radiation of the breast with 50.4 dye plus local boost radiotherapy of the tumor bed Page of ... focus of heightened activity showed up in the right lower axilla A radioactively marked lymph node was found during the preparation of the axilla There were no other foci of heightened activity The...

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Báo cáo y học: "Can a single model explain both breast cancer and prostate cancer?" pps

Ngày tải lên : 13/08/2014, 16:21

... in the absence of androgen is the same as that in the presence of androgen if ionophores are used to cause sufficiently high Ca++ influx [51] In the absence of androgen, the increased amount of ... agonism of mAR along with no agonism of iAR However, if there is a great amount of agonism of mAR along with a small amount of agonism of iAR, then there would still be an increase in RD for PC if the ... present and therefore no decrease in bcl-2 Table shows the effects of the HTHD protocol For PC, the minimum safe physiological level of bioavailable T and the maximum safe physiological level of DHT...

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Báo cáo khoa học: "The combination effect of sodium butyrate and 5-Aza-2''''-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines" pot

Ngày tải lên : 09/08/2014, 04:21

... human colon and breast cancer cell lines were used to determine the effects of the demethylation agent, 5-Aza-2'deoxycytidine (5-aza-DC), and the HDAC inhibitor, sodium butyrate (SB), and the two ... radiation dose and culture time We irradiated the RKO cell line with the different dose of radiation(4G, 6G, 4G + 4G) and cultured the cells for 24 hours, 48 hours and 72 hours Then we analyzed the cell ... 0.001) In the RKO cell line, 56.5% of the cells survived after radiation alone, 47% survived with the addition of 5-aza-DC, and a similar percentage (46%) survived with the addition of SB The combination...

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Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf

Ngày tải lên : 15/02/2014, 04:20

... interval of follow-up Numbers above the bars indicate numbers of events Invasive Cancers Other Than Cancer of the Breast and Uterus (Endometrium) Invasive cancers at sites other than the breast and ... two were in the placebo of invasive breast cancer in the placebo group and three in the group and one was in the tamoxifen group The rate of invasive breast cancer among women in the tamoxifen ... DCIS In view of the cost involved and the effort required to diagnose these tumors and in light of the debate about both the initial and subsequent treatment of patients with DCIS and the putative...

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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

Ngày tải lên : 21/02/2014, 15:20

... 36% of the interaction of the full peptide with the binding cavity of SM3 The sizes of the surfaces were determined using distances between ligand ˚ atoms and protein atoms of less than A These ... a distance of A or less to the ligand The C-terminal part of the peptide (RPAP) has close contacts to the next protein in the crystal cell and is therefore stabilized on the surface of SM3 It ... reference pairs The build-up of the trNOE between Asp2-b and b¢ is much faster than that of the other two reference points indicating diﬀerences of the rotational correlation times of these proton...

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Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer pptx

Ngày tải lên : 05/03/2014, 12:20

... dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that ... effects on the absolute risk of developing breast cancer Thus, the lifetime risk of developing breast cancer is 14.4 percent, whereas the absolute risk of developing breast cancer over the decade ... 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute...

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Familial breast cancer - The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care potx

Ngày tải lên : 15/03/2014, 00:20

... evidence The full guideline (‘Familial breast cancer: the classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care’) gives details of the methods and ... In the context of this guideline: All affected relatives must be on the same side of the family and be blood relatives of the woman and each other In cases of bilateral breast cancer, each breast ... these issues fully so that the woman understands what she can and cannot to modify her risk of breast cancer, and the effect this will have on her risk of other diseases and conditions Many of...

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Factors inﬂ uencing the risk of breast cancer – established and emerging ppt

Ngày tải lên : 15/03/2014, 01:20

... the ovaries) and is essential for the development of the breast, paradoxically oestrogen is also involved in the development of breast cancer via the stimulation and proliferation of breast cancer ... views of the funders and the EU institutions Factors inﬂuencing the risk of breast cancer – established and emerging April 2008 Introduction Most of us will know of someone affected by breast cancer, ... chemicals and provide invaluable insight into the complicated origins of breast cancer I) THE COCKTAIL EFFECT Despite the theory of the role of oestrogen mimicking chemicals in breast cancer, it...

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Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue pdf

Ngày tải lên : 22/03/2014, 17:20

... in their models [19] To obtain more insight into the role of the fat breast tissue, we investigated the independent effects of the size of dense tissue and the size of non-dense tissue in the breast ... non-dense area Therefore, the resulting risk depends on the composition of the breast and not simply on the size of the breast When studying dense breast tissue in relation to breast cancer risk, ... for breast cancer development [3,34] Also, it has often been hypothesized that the area of the dense tissue would reflect the effect of estrogens on the breast, because many determinants of mammographic...

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Guidelines for the early detection and screening of breast cancer ppt

Ngày tải lên : 28/03/2014, 23:20

... be the focus of family life The impact of breast cancer is therefore profound on both the woman diagnosed with the disease and her family Their fear and anxiety over the eventual outcome of the ... examination of the breast in the shower is the method of choice for many women If the breasts are small, the woman should place one hand on her head and examine the breast on that side with the other ... education of professionals focuses on the role of the professional as the initial point of contact between potential cancer patients and the health care system These professionals must be aware of the...

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Báo cáo sinh học: " Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure" potx

Ngày tải lên : 18/06/2014, 19:20

... pressure The fact that 55-75% of patients with premalignant DCIS overexpress HER-2/neu in their tumor lesions and 75% of breast cancers are HER-2/neu negative would suggest the progression of HER-2/neu ... in the expression of HER-2/neu [10] Such failure of the LNCaP to respond to IFN-g was later shown to be due to the lack of JAK1 expression [11] These findings prompted us to determine whether ... suggest potentially negative effects of some immune responses in breast cancer Matkowski and Sheu both showed in cohorts of 88 and 24 patients with operable breast cancer, respectively, that relapse...

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báo cáo hóa học:" Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure" pdf

Ngày tải lên : 20/06/2014, 03:20

... pressure The fact that 55-75% of patients with premalignant DCIS overexpress HER-2/neu in their tumor lesions and 75% of breast cancers are HER-2/neu negative would suggest the progression of HER-2/neu ... in the expression of HER-2/neu [10] Such failure of the LNCaP to respond to IFN-g was later shown to be due to the lack of JAK1 expression [11] These findings prompted us to determine whether ... suggest potentially negative effects of some immune responses in breast cancer Matkowski and Sheu both showed in cohorts of 88 and 24 patients with operable breast cancer, respectively, that relapse...

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báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer" pps

Ngày tải lên : 09/08/2014, 01:24

... skin, and an adequate skin bridge will maintain the distance from the balloon to the skin surface The greater the volume of the balloon, with the attendant compression of adjacent breast tissue, the ... Wang Y, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG): Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year ... All other adverse events were Grade or Discussion The American Society of Breast Surgeons and the American Brachytherapy Society have published guidelines for the screening and selection of patients...

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Báo cáo khoa học: "Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer" pot

Ngày tải lên : 09/08/2014, 03:22

... probable that the association of granulosa cell tumor and the use of tamoxifen for breast cancer is just a random observation and there is no relationship between them As mentioned earlier, the granulosa ... adjuvant therapy in breast cancer [8] Its proven efficacy as a chemotherapeutic agent has led to its prophylactic use in the prevention of breast cancer in healthy women at high risk of developing breast ... responsible for the conception and design for the manuscript, the clinical work, the search for the literature, and the editing work MK helped in the clinical work as well as the literature review...

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Báo cáo khoa học: "Comparison of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assessment for Her-2 status in breast cancer" ppsx

Ngày tải lên : 09/08/2014, 04:21

... in the cases of IHC 3+ is similar with theirs, but there are some differences in the cases of IHC 0, 1+, 2+ The concordance in this study of IHC and 1+ is lower, and IHC 2+ is higher than theirs ... may due to the different sensitivity and specificity of the antibodies and probe used in this study The different sensitivity and specificity of the antibodies and probe need to be further researched ... and 1+ was defined as the number of discrepant IHC and 1+ cases divided by the total number of IHC and 1+ cases and was 19.2% (5/ 26) Following the same way of counting, the discordance rate according...

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